The author’s weight loss surgery led her to start an exercise program that provided her with more muscle tone — and a lot of fun
To exercise or not to exercise? I can almost hear the people reading this article screaming, “NOT!” Truthfully, until about a year ago, I would have been screaming NOT the loudest, the longest and with absolutely no hesitation.
Author Danise Armstrong riding her tricycle.
Living with CMT
Researcher Carmen Bertoni is using DNA-like material to fix flawed genes
When Carmen Bertoni came to the University of Tulane in New Orleans from her native Italy back in 1995 to study the burgeoning science of molecular genetics, she knew she wanted to study genetic disorders but not solely to advance the field. "I wanted to work on something that would potentially be curable within my lifetime," she says.
Dongsheng Duan is tweaking dystrophin genes to improve their therapeutic efficacy, designing better viral vectors in which to package the genes, and aims to treat the heart with gene transfer
By the time Dongsheng Duan finished medical school at West China University of Medical Sciences in Sichuan Province in the late 1980s, he knew he wanted to study biological sciences in the United States. Political turmoil in China temporarily derailed his plans, but in 1993, he left his home country. By the following year, he was at the University of Pennsylvania, working with Katherine High, an...
Charles Gersbach is using “nuclease-based genome correction” to turn flawed dystrophin genes into functional ones
In 2001, Charles Gersbach began his graduate studies in biomedical engineering at the Georgia Institute of Technology in Atlanta, joining a center that was working on constructing semi-artificial muscle, bone and cartilage tissues.
He was interested in constructing new materials and making tissue implants, but what intrigued him more were the genetic underpinnings of tissue growth and...
Hansell Stedman, a surgeon who had two brothers with Duchenne muscular dystrophy, aims to translate lessons from crush injuries into improvements in gene therapy
You don’t have to look far to figure out how Hansell Stedman got interested in Duchenne muscular dystrophy (DMD). His older brother, Holt, and younger brother, Roland, had the disease.
Jeffrey Chamberlain believes that providing new dystrophin genes is the best way to treat Duchenne muscular dystrophy, although combining gene transfer with other strategies interests him.
Jeffrey Chamberlain’s interest in Duchenne muscular dystrophy (DMD) began in 1986, when mutations in the dystrophin gene were first identified as the underlying cause of the disease.
At that time, Chamberlain was working in a lab at Baylor College of Medicine in Houston, trying to find out what was causing weakness in mice that seemed to have some type of muscular dystrophy. He began to think the...