mesoangioblasts

Genetically corrected human stem cells help mice with a disease resembling limb-girdle MD; cell membrane sealants are being studied in Duchenne and other forms of muscular dystrophy

posted on July 3, 2012 - 11:49am
LGMD2D mice benefit from corrected human stem cells A multinational team of scientists successfully transplanted genetically corrected muscle stem cells derived from people with type 2D limb-girdle muscular dystrophy (LGMD2D) into LGMD2D research mice and saw better muscle function in these mice than in similar mice that didn't receive the cells.
posted on September 1, 2008 - 10:07am
QUEST Vol. 15, No. 5
Real progress is being made in supplying functional dystrophin genes to treat Duchenne muscular dystrophy (DMD), a disease in which mutated dystrophin genes keep this critical protein from being produced in muscle fibers.
posted on May 1, 2007 - 4:04pm
QUEST Vol. 14, No. 3
New muscle-generating stem cells isolated from human tissue Researchers at several U.S. and Italian institutions say they’ve isolated from human skeletal muscle a new type of stem cell that they believe could be “ideal” for the treatment of muscular dystrophy. MDA-supported Giulio Cossu at the San Raffaele Scientific Institute in Milan, Italy, and Paolo Bianco of the San Raffaele Biomedical...