corticosteroids

Funding from MDA and three other organizations will allow ReveraGen BioPharma to test its experimental anti-inflammatory drug for Duchenne MD in healthy volunteers

posted on July 17, 2014 - 8:00am
ReveraGen BioPharma, based in Silver Spring, Md., is moving ahead with a phase 1 trial of an experimental compound in development to treat Duchenne muscular dystrophy (DMD), made possible by a $2 million grant from U.S.-based MDA and three United Kingdom-based DMD organizations.

A new MDA grant will defray travel costs for participants in a large-scale trial to find the optimal corticosteroid regimen for boys with Duchenne MD

posted on October 24, 2013 - 2:00pm
Robert Griggs, a professor of neurology at the University of Rochester (N.Y.), has received an MDA grant of $237,316 over three years to support travel costs for North American participants in a large, multinational trial to determine which corticosteroid treatment regimen is best for children with Duchenne muscular dystrophy (DMD).
posted on October 3, 2013 - 9:05am
Quest Vol. 20, No. 4
In kindergarten, Mo Gerhardt played tee ball and soccer, and while his hand-eye coordination was excellent, his strength wasn’t. Matthew (“Mo”) Gerhardt of Bath, Mich., will be 36 years old this fall.

MDA grant will support a study of prednisone in 25 boys with Duchenne muscular dystrophy who are less than 2½ years old

posted on August 20, 2013 - 5:00am
Pediatric neurologist Anne Connolly has received an MDA grant to study the effects of prednisone on Duchenne muscular dystrophy in very young children. MDA has awarded a grant to Anne Connolly, a pediatric neurologist at Washington University in St.

Many MDA grants for research in myasthenia gravis aim to prevent the immune system from attacking needed muscle proteins while allowing it to fight infection

posted on June 25, 2013 - 11:00am
It can start with nothing more than a drooping eyelid or a slight slurring of speech, either of which can come and go and improve with rest. But it can progress, often gradually over weeks or months, to affect all the voluntary muscles, including those controlling breathing. Weakness may be minimal early in the morning after a good night's sleep and worsen throughout the day, especially after...

Researchers have developed a new, two-step process for screening newborn babies for Duchenne MD and possibly other muscular dystrophies

posted on March 2, 2012 - 9:37am
Update 5/21/12: A podcast on this topic is now available; see Podcast Explores Newborn Screening for DMD.

Yearlong, MDA-supported study comparing two prednisone dosing schedules in Duchenne MD found similar benefits and side effects

posted on July 20, 2011 - 9:52am
A one-year, MDA-supported study comparing a weekend-only prednisone treatment schedule with a daily prednisone schedule in boys with Duchenne muscular dystrophy (DMD) has found that the two treatment regimens provide about the same benefits and have approximately the same side-effect profile.
posted on March 31, 2011 - 11:41am
QUEST Vol. 18, No. 2
"I was always interested in the application of genetics to human problems," says Eric Hoffman, a molecular geneticist and MDA research grantee who directs the Center for Genetic Medicine Research at Children's National Medical Center in Washington. In the mid-1980s, as he was finishing his doctorate in biology at Johns Hopkins University, Hoffman says, "I began looking around for a human...