signs and symptoms

A look at symptoms, diagnosis, treatments and current MDA-supported research into this complex autoimmune disorder

posted on June 15, 2015 - 1:01pm
In recognition of June being National Myasthenia Gravis Awareness Month, MDA is examining the disease from several perspectives. This article offers an overview of signs, symptoms, diagnosis and treatments for myasthenia gravis (MG), as well as information on drugs that people with MG should avoid.

Investigators conducting an online survey to gather information from people with inclusion-body myositis report early results and ask a few more questions

posted on November 27, 2013 - 5:00am
Investigators conducting an online survey launched in January 2013 to gather anonymous information from people with inclusion-body myositis (IBM) are now reporting preliminary results and are asking the original respondents to complete a short supplementary survey.

MDA-supported researchers have conducted a study of the perceived effects of congenital and childhood-onset type 1 myotonic dystrophy on those with the disorder

posted on August 28, 2013 - 9:55am
Communication difficulties, social role limitations, problems with mobility and walking, and cognitive impairment were the most frequently mentioned themes in open-ended interviews conducted with people affected by congenital-onset or childhood-onset type 1 myotonic muscular dystrophy (MMD1, or DM1) or their parents.

Many MDA grants for research in myasthenia gravis aim to prevent the immune system from attacking needed muscle proteins while allowing it to fight infection

posted on June 25, 2013 - 11:00am
It can start with nothing more than a drooping eyelid or a slight slurring of speech, either of which can come and go and improve with rest. But it can progress, often gradually over weeks or months, to affect all the voluntary muscles, including those controlling breathing. Weakness may be minimal early in the morning after a good night's sleep and worsen throughout the day, especially after...

A challenging and multifaceted disease

posted on April 9, 2012 - 12:05pm
QUEST Vol. 19, No. 2
As far back as Carla Licon can remember, her mother had difficulty opening jars and walking long distances. Licon’s mother wore ankle braces, and she also had an unusual symptom known as "myotonia," the inability to relax muscles, such as a clenched hand, at will. Licon, who is 31 and lives in Victoria, Texas, thinks these symptoms started when her mother was in her 20s. Later, her mother’s...

The complex effects of MMD on the brain's sleep-wake cycles and on the respiratory and airway muscles can cause sleepiness that's challenging to diagnose and treat

posted on April 9, 2012 - 11:06am
QUEST Vol. 19, No. 2
Thirty-two-year-old Doug Hayes has struggled with some of the cognitive and social features of type 1 myotonic dystrophy (MMD1 or DM1) most of his life. But there’s something else that’s contributed to his difficulties with jobs and schooling: daytime sleepiness. Doug recently had a job scanning documents, his father says, but his daytime sleepiness interfered.
posted on January 1, 2011 - 2:20pm
QUEST Vol. 18, No. 1
From childhood science classes, you may remember the periodic table listing all the known chemical elements. You might also recall, in approximately the center of the table, the symbol “Fe” signifying the metal iron. Produced inside large stars in distant space, iron is the most common element on Earth. From earliest times, humans have used it in everything from paint pigments, cookware and tools...
posted on March 31, 2010 - 2:27pm
QUEST Vol. 17, No. 2
Forty-one-year-old Sandy Doak remembers that she was never athletic, couldn’t do sit-ups, and always had trouble finishing physical tasks. But, she says, “I never really thought I had anything wrong. I just thought I was awkward. I knew I was weaker than others. That had pretty much lasted most of my life.” Sometimes she found herself the object of ridicule, which, while friendly, wasn’t...