Kennedy's Disease / X-Linked SBMA

Stanford University is collecting samples of blood, muscle and other tissues from people with neuromuscular disorders for use in research

posted on January 7, 2015 - 12:06pm
Ever wondered how someone with a neuromuscular disorder in his or her family might contribute to research efforts in this field?

Treatment with IGF1 improved motor function, slowed weight loss, improved muscle health and increased survival time in mice with a disease resembling spinal-bulbar muscular atrophy

posted on September 10, 2012 - 5:00am
Mice with a disease resembling spinal-bulbar muscular atrophy (SBMA, or Kennedy disease) that were treated with a compound based on insulin-like growth factor 1 (IGF1) had better motor function, slower weight loss, healthier muscles and longer survival time than mice that received an inactive substance, an MDA-supported research team has reported.

Participants will be randomly assigned to a strength or stretching exercise program, and undergo multiple evaluations

posted on August 9, 2011 - 12:00am
Update June 19, 2013: This study is nearing completion. However, enrollment is still open and additional participants are needed.

Research items about Friedreich's ataxia, myasthenia gravis, mitochondrial myopathies, type 1 myotonic dystrophy, gene therapy and gene modification

posted on July 7, 2011 - 10:28am
Edison drugs target FA, mitochondrial diseases

Researchers at the University of Michigan are studying why some people identify themselves as disabled and others do not

posted on June 1, 2011 - 4:30pm
Researchers at the Psychology of Disability Lab at the University of Michigan in Ann Arbor are exploring the social identity of people with disabilities through a short, anonymous, Web-based questionnaire. The lab's Disability Identity Project is being headed by principal investigator Adena Rottenstein, a doctoral candidate in psychology. The study closes the week of Aug. 22, 2011.

News about research in Charcot-Marie-Tooth disease, congenital myasthenic syndromes, Duchenne/Becker MDs, Friedreich's ataxia, Pompe disease and spinal-bulbar muscular atrophy

posted on February 10, 2011 - 11:09am
Charcot-Marie-Tooth disease

Neuron degeneration in spinal-bulbar muscular atrophy might be blocked by targeting an overactive androgen receptor protein and its interactions with other proteins

posted on September 28, 2010 - 3:48pm
Overactive function of normal androgen receptor protein and its interaction with disease-modifying "partner proteins" has been implicated as the specific underlying cause of motor neuron (nerve cell) degeneration and death in spinal-bulbar muscular atrophy (SBMA, or Kennedy disease).

A trial of a drug that reduces testosterone levels did not improve swallowing in men with spinal-bulbar muscular atrophy

posted on August 30, 2010 - 12:51pm
 Reducing testosterone levels in a large-scale trial in men with spinal-bulbar muscular atrophy (SBMA, or Kennedy disease) did not significantly affect swallowing function, despite earlier indications that it might improve this aspect of the disease.