A study of whether MRI or MRS imaging of leg muscles can be used to follow the progression of Duchenne MD is open in three states
A multicenter study of the use of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) to measure the progression of Duchenne muscular dystrophy (DMD) is open at sites in Florida, Oregon and Pennsylvania for boys with DMD who meet study criteria.
The study, known as ImagingDMD, is a joint effort of the University of Florida, the Children's Hospital of Philadelphia, the University of Pennsylvania, Oregon Health and Science University and Shriners Hospital for Children in Portland.
It's supported by the National Institutes of Health (NIH) and is being conducted to learn more about the changes that occur in the muscles of the lower legs in boys with DMD and to develop an improved imaging procedure to follow disease progression.
MRI and MRS are noninvasive imaging procedures that allow researchers to take pictures of what's going on inside the body without invading the body (such as through a muscle biopsy procedure).
Prospective participants must:
Prospective participants must not:
Overall Project Coordinator and Gainesville Site Coordinator
Portland Site Coordinator
Philadelphia Site Coordinator
For more details about this study, see ImagingDMD; and/or see Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy; or enter NCT01484678 in the search box at ClinicalTrials.gov.
About Clinical Trials
A clinical trial is a test, in humans, of an experimental treatment. Although it's possible that benefit may be derived from participating in a clinical trial, it's also possible that no benefit, or even harm, may occur.