Zinc finger protein 1 (ZPR1) appears to be a 'protective modifier' of spinal muscular atrophy, making it a potential target in the development of therapies
posted on March 27, 2012 - 10:44am
Adequate levels of zinc finger protein 1 (ZPR1) appear to be a "protective" modifier of spinal muscular atrophy (SMA), an MDA-supported team of scientists has reported.
Modifiers influence disease onset and severity by changing various biological pathways.
The identification of ZPR1 as a modifier reveals a potential target for therapy development and also sheds light on the mechanisms that drive...