A new zebrafish research model may speed myofibrillar myopathy research; published results of a gene transfer study in LGMD are now accessible
Update (Aug. 8, 2012): This story was updated to reflect the availability of a podcast on the dysferlin gene transfer study.
Zebrafish research models mimic myofibrillar myopathy
Are myelin and axons 'talking' to each other — and what are they saying?
MDA-supported research in Charcot-Marie-Tooth disease is focused on figuring out what goes wrong at the molecular level in CMT-affected axons or the myelin sheaths that surround them, rather than on attempting to fix the problem directly or preserving nerve function in spite of it. A central theme emerging from the last decade of research is that myelin and axons require constant signals from...
A screen of more than 1,120 chemicals in dystrophin-deficient zebrafish revealed three candidates for further testing as treatments for Duchenne or Becker MD
Three small molecules that normalize muscle structure and function and improve survival in dystrophin-deficient zebrafish have been identified by scientists at Children's Hospital Boston, Harvard Medical School, and Alaska Fisheries Science Center in Juneau.
The three chemicals, which already are approved for other medical uses, were found to increase survival and normalize muscle structure and...