Stanley Appel

Progress in ALS research requires a free flow of information between MDA-supported laboratory investigators and leaders in the drug-development industry

posted on April 21, 2015 - 9:17am
ALS, also known as amyotrophic lateral sclerosis and Lou Gehrig’s disease, is among the most feared diseases facing people in the U.S. and worldwide. In ALS, the motor neurons — the nerve cells of the brain and spinal cord that control muscle action — mysteriously deteriorate, often within just a few years, leaving behind orphaned muscle fibers. Without signals from motor neurons, voluntary...

Ten leaders in the field of ALS research put their heads together on Oct. 24, 2009

posted on October 30, 2009 - 5:18pm
  An all-day "think tank" to consider priorities for amyotrophic lateral sclerosis (ALS) research based on the latest information was conducted with ten of the leading scientists and clinicians in the field and senior MDA staff in Tucson, Ariz., on Saturday, Oct. 24, 2009. Each specialist introduced his or her area of expertise and led an approximately 20-minute discussion, gathering input...

Researchers add support to evidence that the blood-spinal cord barrier is abnormally leaky in ALS

posted on May 27, 2009 - 9:00pm
Proteins that keep large molecules from moving freely across blood-vessel walls in the spinal cord appear to be deficient in people with ALS (amyotrophic lateral sclerosis), MDA-supported researchers say. They don't yet know, however, whether a lower-than-normal level of some of these so-called "tight junction" proteins, is helpful or harmful in the disease process.
posted on May 1, 2008 - 9:39am
QUEST Vol. 15, No. 3
MDA has an Ace in celebrity supporter Singer, Grammy-nominated songwriter and actor Ace Young has a notable repertoire of philanthropy for his 27 years. Now he’s added MDA to the list of charitable endeavors he wants to help.
posted on March 1, 2006 - 9:35am
QUEST Vol. 13, No. 2
The MDA Board of Directors has three outstanding physicians, each of whom generously shares his own area of expertise — Leon I. Charash in pediatric neurology, R. Rodney (Rod) Howell in genetics and Stanley H. (Stan) Appel in amyotrophic lateral sclerosis. Their knowledge and experience help to keep the Association on track toward its primary mission: finding treatments and cures for...