MDA-supported researchers in Ottawa have identified a biological pathway that could become a new treatment avenue in spinal muscular atrophy (SMA).
posted on February 22, 2010 - 10:08am
MDA-supported researchers at the University of Ottawa and Ottawa Hospital Research Institute (OHRI) have identified a biological pathway that may prove useful in developing treatments for spinal muscular atrophy (SMA).
Lamin defects may disrupt nerve-muscle signals in Emery-Dreifuss MD
posted on January 28, 2009 - 6:16pm
Mutations in the lamin A/C gene on chromosome 1 and the emerin gene on the X chromosome both can cause Emery-Dreifuss muscular dystrophy (EDMD), but the precise mechanisms by which they do so are still being identified.
Now, a multinational team has found that, in mice with an EDMD-like disease, lamin protein defects interfere with the way cell nuclei normally localize in skeletal-muscle fibers...