mystery mechanism that causes SBMA spinal-bulbar muscular atrophy

Neuron degeneration in spinal-bulbar muscular atrophy might be blocked by targeting an overactive androgen receptor protein and its interactions with other proteins

posted on September 28, 2010 - 3:48pm
Overactive function of normal androgen receptor protein and its interaction with disease-modifying "partner proteins" has been implicated as the specific underlying cause of motor neuron (nerve cell) degeneration and death in spinal-bulbar muscular atrophy (SBMA, or Kennedy disease).

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