muscle stem cells

Researchers are pursuing several strategies to identify or modify stem cells that can be used to repair damaged muscle fibers

posted on June 14, 2012 - 10:21am
Update (July 10, 2012) — This story was updated to reflect the availability of a podcast with MDA research grantee Emanuela Gussoni, who discusses the development of stem-cell-based treatments for muscular dystrophies.

posted on March 31, 2010 - 3:50pm
QUEST Vol. 17, No. 2
Featured in this article: Charcot-Marie-Tooth disease * Duchenne and Becker MD * Hypokalemic periodic paralysis * Limb-girdle muscular dystrophy * Myoshi myopathy * Myotonic dystrophy * Oculopharyngeal muscular dystrophy * Spinal muscular atrophy
posted on July 1, 2009 - 3:09pm
QUEST Vol. 16, No. 3
Two longtime MDA grantees receive prestigious award On May 3, 2009, molecular biologist Louis Kunkel at Children’s Hospital in Boston and Harvard University, and biophysicist Kevin Campbell at the University of Iowa, received the prestigious March of Dimes Prize in Developmental Biology. The prize includes a $250,000 cash award.

The WNT7a protein increases proliferation of muscle repair cells, a finding that could have implications for MD treatment

posted on June 15, 2009 - 10:12am
In experiments in mice, Michael Rudnicki, an MDA grantee at the Sprott Center for Stem Cell Research at Ottawa Hospital Research Institute (OHRI), and colleagues, found the WNT7a protein stimulates muscle repair by causing proliferation (an increase in number) of "satellite stem cells." They say the protein probably operates similarly in humans. The findings were published June 5, 2009, in the...

Two MDA-supported groups have recently made great strides in stem cell therapies for muscle disease

posted on January 1, 2007 - 1:16pm
QUEST Vol. 14, No. 1
Stem cells treat MD in dogs MDA grantee Giulio Cossu, director of the Stem Cell Research Institute of the San Raffaele Scientific Institute of Milan (Italy), was part of an Italian and French research team that restored mobility to two dogs and stabilized function in a third, using stem cells taken from muscle blood vessels.