Featured in this article: Charcot-Marie-Tooth disease * Duchenne and Becker MD * Hypokalemic periodic paralysis * Limb-girdle muscular dystrophy * Myoshi myopathy * Myotonic dystrophy * Oculopharyngeal muscular dystrophy * Spinal muscular atrophy
Two longtime MDA grantees receive prestigious award
On May 3, 2009, molecular biologist Louis Kunkel at Children’s Hospital in Boston and Harvard University, and biophysicist Kevin Campbell at the University of Iowa, received the prestigious March of Dimes Prize in Developmental Biology. The prize includes a $250,000 cash award.
The WNT7a protein increases proliferation of muscle repair cells, a finding that could have implications for MD treatment
In experiments in mice, Michael Rudnicki, an MDA grantee at the Sprott Center for Stem Cell Research at Ottawa Hospital Research Institute (OHRI), and colleagues, found the WNT7a protein stimulates muscle repair by causing proliferation (an increase in number) of "satellite stem cells." They say the protein probably operates similarly in humans. The findings were published June 5, 2009, in the...
Two MDA-supported groups have recently made great strides in stem cell therapies for muscle disease
Stem cells treat MD in dogs
MDA grantee Giulio Cossu, director of the Stem Cell Research Institute of the San Raffaele Scientific Institute of Milan (Italy), was part of an Italian and French research team that restored mobility to two dogs and stabilized function in a third, using stem cells taken from muscle blood vessels.