Muscle Contraction

Much progress but mysteries remain

posted on April 1, 2010 - 2:42pm
Back in 1956, investigators at the National Institutes of Health described five members of a three-generation family, all of whom had experienced delayed motor development, with walking not achieved until age 4 or 5, and difficulty climbing stairs, running and changing from a back-lying to a sitting position.

Cardiac actin compensated for the loss of skeletal-muscle actin in mice with a disease resembling nemaline myopathy

posted on June 15, 2009 - 9:00pm
A protein present in skeletal muscles during fetal development and in the heart after birth can apparently compensate for a similar protein that's missing in a small percentage of patients with the muscle disease known as nemaline myopathy. MDA research grantee Nigel Laing at the University of Western Australia in Perth was part of a multinational team of scientists, who published their findings...