mouse model

MDA has awarded $300,000 to Children's National Medical Center to maintain a valuable research mouse testing facility

posted on March 7, 2012 - 6:00am
The Muscular Dystrophy Association has given a $300,000 grant to the Center for Genetic Medicine Research (CGMR) at Children’s National Medical Center in Washington, D.C., to continue standardized and reliable preclinical studies of neuromuscular diseases.

Treatment with the protein prolactin improved motor function and enhanced survival time in mice with a disease resembling severe SMA

posted on August 8, 2011 - 3:02pm
The administration of a protein called prolactin has been shown to slow weight loss, improve motor function and increase life span by approximately 70 percent in mice with a disease resembling a severe form of spinal muscular atrophy (SMA). Prolactin is a hormone whose primary function is to promote milk production in women who are breastfeeding.

MDA-supported scientists found raising SMN protein levels conferred significant benefits on young SMA mice, even after symptom onset

posted on August 4, 2011 - 9:40am
The "window of opportunity" for treating infants at risk of developing spinal muscular atrophy (SMA) may not be as narrow as some experts have feared, new experiments in mice suggest.