motor neurons

Animal studies suggest that spinal muscular atrophy may result primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought

posted on October 17, 2012 - 12:31pm
Results from a study in fruit flies conducted by scientists in the Motor Neuron Center at Columbia University Medical Center in New York suggest that spinal muscular atrophy (SMA) — commonly thought to be a disease of muscle-controlling nerve cells called motor neurons — instead results from the dysfunction of motor circuits (networks made up of different types of specialized neurons that...

Repligen soon will begin a first-ever human trial of a drug created specifically for spinal muscular atrophy;  FDA grants fast track designation

posted on May 20, 2011 - 11:13am
In a historic first, biotech company Repligen Corp., of Waltham, Mass., has received approval from the U.S. Food and Drug Administration (FDA) to begin a phase 1 clinical trial of the experimental drug RG3039 for spinal muscular atrophy (SMA).

An ALS Therapy Development Institute Webcast summarizes research progress as of July 2009

posted on July 29, 2009 - 12:15pm
On July 16, 2009, the MDA-supported ALS Therapy Development Institute (ALS TDI) gave its quarterly research update in a Webcast that's now archived on the Institute's site and accessible to all who register. (See Research Update Q209.)