Curcumin (which makes the spice turmeric yellow) benefited mice with a disease resembling type 1B Charcot-Marie-Tooth
Mice with a genetic mutation in the myelin protein zero (MPZ) gene, which develop a disease resembling human type 1B Charcot-Marie-Tooth disease (CMT1B), benefited from treatment with curcumin and curcumin derivatives, researchers announced April 15, at the 2010 meeting of the American Academy of Neurology (AAN), held in Toronto.
Investigators from Wayne State University found that five genetic subtypes of Charcot-Marie-Tooth disease accounted for more than 99 percent of diagnoses
Editor's note: This story was updated Feb. 4, 2011, to reflect the availability of a paper and editorial on this subject in Annals of Neurology.
Results of genetic testing done at Wayne State University in Detroit of more than 1,000 people suspected of having Charcot-Marie-Tooth (CMT) disease were presented by MDA grantee Michael Shy and colleagues April 14, 2010, at the annual meeting of the...
Q: What could possibly be bad about children with neuromuscular diseases living longer life spans than has been common in the past?
A: As these children become adolescents and then adults, they encounter a medical system and society that are not prepared to accommodate them.
The following article contains items about: Friedreich's ataxia, Charcot-Marie-Tooth disease, myotonic muscular dystrophy type 1, amyotrophic lateral sclerosis, Emery-Dreifuss muscular dystrophy and distal muscular dystrophy (Miyoshi myopathy)
Jury still out on vitamin C for treating CMT1A symptoms
A recent trial has shown inconclusive results from various doses of vitamin C (ascorbic acid) in patients with the peripheral nerve disease type 1A Charcot-Marie-Tooth disease (CMT1A), and the jury remains out on this form of treatment, says Michael Shy, an MDA grantee at Wayne State University in Detroit.
From clear-cut endings to complex beginnings
"Clinical medicine is first and foremost the study of the difficult aspects and complexities of diseases. When a patient calls on you, he is under no obligation to have a simple disease just to please you." — Jean-Martin Charcot in a lecture to medical students, 1887