Matthew Meriggioli

High levels of misplaced proteins may worsen the disease process in myasthenia gravis

posted on August 25, 2009 - 12:22pm
Stepped-up production of fragments of acetylcholine receptors, the microscopic "landing pads" on muscle fibers that normally help process signals from the nervous system, may provoke the immune system and worsen myasthenia gravis (MG), new research shows. In mice with an MG-like disease, these receptor fragments (which are proteins) are abundant but nonfunctional, and they end up in the wrong...

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