ion channels

Much progress but mysteries remain

posted on April 1, 2010 - 2:42pm
Back in 1956, investigators at the National Institutes of Health described five members of a three-generation family, all of whom had experienced delayed motor development, with walking not achieved until age 4 or 5, and difficulty climbing stairs, running and changing from a back-lying to a sitting position.

Individuals and families struggle to manage the periodic paralyses, a group of diseases that’s too often misunderstood by teachers, employers and even health professionals.

posted on July 1, 2009 - 3:09pm
QUEST Vol. 16, No. 3
People who know me know I lead an extremely active life,” says Linda Feld of Longwood, Fla. “People don’t see me as somebody on a scooter. I’m Linda, and I do all these things every day, and they know me for me. I tell people that periodic paralysis has become my friend. It’s along for the ride, but it’s not going to rule my life.”

A basic chart

posted on July 1, 2009 - 3:04pm
QUEST Vol. 16, No. 3
The Periodic Paralyses Disorder Hyperkalemic Periodic Paralysis Hypokalemic Periodic Paralysis Andersen-Tawil Syndrome

A report on disease management and research as of July 2009

posted on July 1, 2009 - 2:54pm
QUEST Vol. 16, No. 3
This “In Focus” report is part of a series of MDA comprehensive reports about the latest in neuromuscular disease research and management. This report focuses on the periodic paralyses, a group of disorders that result from malfunctions in so-called ion channels, microscopic tunnels that make possible high-speed movement of electrically charged particles across barriers inside cells and between...