induced pluripotent stem cells

Mice with a disorder similar to Duchenne muscular dystrophy showed improved muscle strength and structure following treatment with genetically corrected cells derived from their own skin cells

posted on March 21, 2013 - 5:00am
A therapeutic strategy that combines gene therapy and stem cell transplantation has shown encouraging results in mice with a disorder mimicking Duchenne muscular dystrophy (DMD).

Genetically corrected human stem cells help mice with a disease resembling limb-girdle MD; cell membrane sealants are being studied in Duchenne and other forms of muscular dystrophy

posted on July 3, 2012 - 11:49am
LGMD2D mice benefit from corrected human stem cells A multinational team of scientists successfully transplanted genetically corrected muscle stem cells derived from people with type 2D limb-girdle muscular dystrophy (LGMD2D) into LGMD2D research mice and saw better muscle function in these mice than in similar mice that didn't receive the cells.

News about research in congenital myasthenic syndromes, Duchenne and limb-girdle muscular dystrophies, Pompe disease and induced pluripotent stem cells

posted on February 25, 2011 - 2:34pm
Congenital myasthenic syndromes A multinational team of scientists has identified mutations in the gene for glutamine-fructose-6-phosphate transaminase 1 (GFPT1) as responsible for some forms of a congenital myasthenic syndrome (CMS).