heart health

A European trial in Friedreich’s ataxia finds that combining two experimental therapies improves heart health and neurological function

posted on October 20, 2010 - 11:31am
Results from a clinical trial conducted in Spain involving 20 individuals with Friedreich's ataxia (FA) show that a combination therapy using two drugs, idebenone and deferiprone (DFP), demonstrated a "stabilizing effect" in neurological function and reduced abnormal heart-muscle enlargement in participants who received the two-drug combo for a period of 11 months.

Foreseeing the future of cardiac care in MD

posted on May 1, 2006 - 2:48pm
QUEST Vol. 13, No. 3
In most forms of muscular dystrophy, there are two sets of muscles that are damaged — the respiratory and cardiac — for which compensation is crucial but so far inadequate. Respiratory function can be aided considerably by assisted ventilation, and cardiac function can be prolonged with various treatments. But the Holy Grail of treatment for muscular dystrophy is a systemically administered agent...

Frequently asked questions about cardiac problems in neuromuscular disease

posted on April 1, 1999 - 5:00pm
Cardiac problems are common in several neuromuscular disorders. They can be quite serious, particularly in Duchenne and Becker muscular dystrophy (DMD and BMD). In this, the first of a two-part series, we'll explore cardiomyopathy, the type of heart problem that's found most often in DMD and BMD and also occurs in some other neuromuscular conditions. (Read Part 2 of this series.)