full-length SMN

When mice with an SMA-like disease received a synthetic antisense molecule, they made more full-length SMN protein; newborn mice grew longer tails

posted on July 14, 2010 - 2:05pm
Scientists have found that mice with a disease resembling a mild form of spinal muscular atrophy (SMA) known as SMA type 3 showed more production of a needed protein in their spinal cords and more normal-looking ears and tails after treatment with a gene-modifying molecule that researchers hope could become a treatment for human SMA. About the new findings
posted on April 1, 2009 - 7:08am
QUEST Vol. 16, No. 2