female carriers

posted on December 1, 2001 - 12:52pm
Many neuromuscular diseases are genetic diseases, meaning they're caused by defective genes, and can be passed from one generation to the next. Understanding the facts about a genetic disease is important for family planning and for peace of mind. But it's a challenging task, made more difficult by common misconceptions about genetic diseases.

When DMD carriers have trouble of their own

posted on December 1, 1998 - 4:37pm
The reasoning is sound: A female has two X chromosomes to a male's one, so she has a built-in "backup" if anything should go wrong on either of her two Xs. She can be a "carrier" of an X-linked disease, because she can give a flawed X chromosome to her sons, who, having only one X, will likely develop an X-linked disorder. DMD is one of many X-linked diseases, such as two kinds of hemophilia...