DMD-affected dogs

A compound that seals cell membranes stopped progression of heart degeneration in dogs with a DMD-like disease

posted on March 22, 2010 - 2:19pm
A synthetic compound that seals cellular membranes has been found to stop the progression of heart-muscle destruction in dogs with a disease closely resembling human Duchenne muscular dystrophy (DMD), MDA-supported researchers have found.

Success of 'exon-skipping' strategy in dogs bodes well for treatment of human DMD

posted on March 17, 2009 - 9:00pm
Scientists at Children's National Medical Center in Washington, Carolinas Medical Center in Charlotte, N.C., and the National Center of Neurology and Psychiatry in Tokyo, have successfully treated dogs with a disease closely resembling Duchenne muscular dystrophy (DMD) , using a molecular treatment strategy called "exon skipping." The strategy is simultaneously under development in human patients.