connection between ALS and inclusion-body myopathy associated with Paget's disease of bone and/or frontotemporal dementia IBMPFD

VCP gene mutations have been linked to some cases of inherited ALS; VCP mutations also are known to cause a form of inclusion-body myopathy 

posted on December 22, 2010 - 9:53am
A multinational study group, using cutting-edge "exome sequencing" technology, has uncovered five mutations in the valosin-containing protein (VCP) gene and implicated them as molecular causes of some familial forms of ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease).

New content is being added every day. Please check back again.