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Pharmaceutical company Eli Lilly is conducting a trial of tadalafil, which may help regulate blood flow to muscles, in some 300 boys with Duchenne MD

posted on December 11, 2013 - 11:18am
Multinational pharmaceutical company Eli Lilly is conducting a phase 3 trial of the drug tadalafil in approximately 300 boys with Duchenne muscular dystrophy (DMD) who are 7-14 years old, able to walk, have adequate cardiac function and meet other study criteria.

People with Becker MD are invited to participate in a trial to determine whether a drug that increases nitric oxide levels can improve blood-flow regulation

posted on October 14, 2013 - 5:00am
Update (Jan. 7, 2014): This trial is now closed to new participants. A new drug trial is now under way at Cedars-Sinai Medical Center in Los Angeles for men with Becker muscular dystrophy (BMD) who meet study criteria.

Researchers invite men with Becker MD (ages 15-50) who meet study criteria to participate in a trial to determine whether tadalafil can improve exercise tolerance

posted on October 7, 2013 - 5:00am
Update (May 7, 2014): This trial is now closed to new participants.====================================================================================== original story: A new trial of tadalafil (Cialis), a drug that dilates blood vessels, is now under way at Cedars-Sinai Medical Center in Los Angeles for men with Becker muscular dystrophy (BMD) who meet study criteria.

An MDA-supported study shows that tadalafil, used to treat erectile dysfunction and pulmonary hypertension, enhances blood flow to exercising forearm muscles in Becker MD

posted on November 28, 2012 - 12:00pm
Update (Sept. 5, 2013): This news item was updated to reflect that none of the trials listed is currently open to new participants.

An MDA-supported study of tadalafil, a drug that may improve blood flow to exercising muscles in people with Becker MD, is seeking 12 additional participants

posted on October 2, 2012 - 4:31pm
Update (Nov. 9, 2012): This story has been updated to reflect that recruitment for this study ends Dec. 31, 2012. An MDA-supported, short-term trial of the vasodilating drug tadalafil (Cialis) in teens and men with Becker muscular dystrophy (BMD) has undergone some minor restructuring and is now open to 12 additional participants.
posted on March 31, 2011 - 11:42am
QUEST Vol. 18, No. 2
Ronald Victor admits it: He never set out to study muscular dystrophy. As an adult cardiologist specializing in hypertension (high blood pressure) and neurologic control of cardiovascular mechanisms, he’s a relative latecomer to the muscle field, but far from a reluctant one.
posted on July 1, 2010 - 9:30am
QUEST Vol. 17, No. 3
Featured in this issue: Tadalafil tested in men with BMD * Tests of ACE031 in boys with DMD begin * New tools to measure progression of CMT in children * Idebenone posts disappointing results in FA For information about active trials in your disease, go to www.clinicaltrials.gov, select Search for Clinical Trials, and enter the disease name in the search box.

The vasodilating drug tadalafil (Cialis) will be tested in men with Becker muscular dystrophy to see if it improves blood flow to forearm muscles

posted on March 24, 2010 - 9:15am
Update (Oct. 8, 2012): This story has been updated to reflect that the tadalafil trial in BMD has been slightly revised and is now open. In June 2012, it had temporarily closed to new participants. The investigators say the revised trial design was necessary because they were unable to obtain access to the MRI machine for the time periods that were necessary in the first design.